Two Postdoc positions in Neuroendocrinology Single Cell Genomics

University of Copenhagen

Denmark

Two Postdoc positions in Neuroendocrinology Single Cell Genomics

Novo Nordisk Foundation Center for Basic Metabolic Research

Faculty of Health and Medical Sciences

University of Copenhagen

 

We are looking for two highly motivated and dynamic researchers for two Postdoc positions to start as soon as possible or after agreement.

 

Background

The Novo Nordisk Foundation Center for Basic Metabolic Research (CBMR) was established in 2010 to conduct fundamental research on metabolism. It is part of the Faculty of Health and Medical Sciences, University of Copenhagen. The Center has around 200 employees from all over the world. We moved into new laboratories, offices and meeting rooms in the Maersk Tower in summer 2017. You can read more about us at http://cbmr.ku.dk.

 

The positions available are in the Central Regulation of Metabolism Group headed by Associate Professor Tune H. Pers. The research group investigates molecular processes that regulate energy balance and glucose control and develops computational tools to prioritise cell type specific risk pathways underlying metabolic traits. You can read more about the research of the Pers Group at https://cbmr.ku.dk/research/human-genomics-and-metagenomics-in-metabolism/pers-group/.

 

Project description

The postdoctoral fellows will analyse large-scale single cell transcriptomics and single cell epigenetics data of the mammalian brain in the context of metabolic health and disease (both projects are generously funded).  

 

The work will be focused on identifying central nervous system mechanisms underlying obesity-, and diabetes pathogenesis and remission. Towards that aim, the successful applicants will leverage in vivo mouse studies, single nuclei RNA sequencing and single nuclei Assay for Transposase-Accessible Chromatin using sequencing (ATAC-seq) to study metabolic disease in the context of mouse and human brain development. Mouse and human single cell data will be integrated with large-scale human genetics data from the GIANT consortium and Danish cohorts (>200,000 deeply phenotyped individuals). Our research group is young and international (started in 2016; 4 PhD Fellows and 2 Postdocs; 4 nationalities), interdisciplinary (human biology, computational biology, applied math, neuroscience) and closely linked to leading international research groups in the area of metabolic research (Professor Michael W. Schwartz, University of Washington, USA) and human stem cell development (Dr. Agnete Kirkeby, Danish Center for Stem Cell Research, University of Copenhagen, Denmark).

 

Profile

We are looking for two highly motivated and enthusiastic scientists with the following competencies and qualifications:

 

The ideal candidates combine:

  • A PhD degree in biomedical or natural sciences

  • Solid expertise in programming (Python, R, machine learning)

  • Experience in analysis of single cell transcriptomics and epigenetics data

  • Experience in handling animals (dissection of brain tissue and dissociation of cells)

  • Solid experience in applied statistics would compensate for lack of experience in animal handling

  • Basic understanding of human genetics

  • Basic understanding of developmental neuroscience

  • An ambitious, independent and critical mind-set

  • An interest in co-supervising PhD Fellows

  • Excellent English communication skills, both written and oral 

Terms of employment

The two postdoc positions are full-time positions for 2 years. Starting date is as soon as possible or after agreement.

 

Salary, pension and terms of employment will be in accordance with the agreement between the Danish Ministry of Finance and AC (Danish Confederation of Professional Associations). Depending on qualifications, a supplement may be negotiated.

 

Non-Danish and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark the last 10 years.

 

The positions are covered by the “Memorandum on Job Structure for Academic Staff at the Universities” of June 28, 2013.

 

Questions

For further information about the position, please contact Associate Professor Tune H. Pers by email tune.pers@sund.ku.dk. For questions regarding the recruitment procedure, please contact SUND HR CBMR by email mlr@sund.ku.dk.

 

International applicants may find these links useful: www.ism.ku.dk(International Staff Mobility) and https://www.workindenmark.dk/.

 

Application procedure

Your online application must be submitted in English by clicking ‘Apply now’ below. Furthermore, your application must include the following documents/attachments – all in PDF format:

  • Motivated letter of application (max. one page)

  • Curriculum vitae (maximum of 2 pages; your ORCID must be included)

  • Full list of publications (journal impact factors at publication date must be included)

  • References (name and contact details of at least two references) 

Application deadline: 8 March 2019 at 23.59pm CET.

 

We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.  

 

The further process

After the expiry of the deadline for applications, the authorised recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether an unbiased assessor has passed their application for assessment. Once the assessment work has been completed, each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

 

You can read about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/.  

 

The applicants will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.  

 

The University of Copenhagen wishes to reflect the diversity of society and welcome applications from all qualified candidates regardless of personal background.  


In your application, please refer to Professorpositions.com

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