Post Doctoral Position in Neuroscience

University of Zurich


Dept. of Neurosurgery, USZ, UZH

Postdoc in neurovascular unit and astrocyte biology
100 %

Our lab is interested in understanding the biology of the neurovascular unit in health and disease.

Your responsibilities

The fellow will study whether mutations in genes causing neurodegenerative disease primary familial brain calcification have a direct effect on astrocyte development, end-feet polarization, and functions. It is a continuation of a project that has been running in our lab for several years (Literature: Zarb et al (Brain, 2019) PMID: 30805583; Keller et al (Nature Genetics, 2013) PMID: 23913003).

Your profile

We are looking for a highly motivated and an independent researcher for a 3 year postdoc position. Applicants should hold a PhD in life sciences (preferably have a glia/neuroscience background). An experience with mouse handling and breeding transgenic mouse lines is required. Techniques will include confocal microscopy, induced-pluripotent stem cell technology, cell culture, single-cell RNA sequencing, in vivo gene delivery using viral vectors, high content image analysis, calcium imaging with genetically encoded calcium indicators on acute brain slices.

What we offer

The position is funded by the Synapis Foundation. We offer varied work in an international environment. Z├╝rich University has excellent core facilities providing support in a wide array of research fields.

Place of work

Department of Neurosurgery, USZ, UZH, Wagistrasse 12, Zurich

Start of employment

Employment start date to be mutually agreed. Please submit your application by February 29, 2020. Please send your application as a single PDF file including a cover letter stating your motivation for this position, a CV, a reference letter and copies of degrees.

Further information

Mrs. Dr. Annika Keller (

In your application, please refer to


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