Post Doctoral Research Associate in Applied Biocatalysis

University of York Department of Chemistry

United Kingdom

Post Doctoral Research Associate in Applied Biocatalysis

Based at:University of York
Hours of work:Full-time
Contract status:Fixed term
Salary:32,817 - 40,322
Posted Date:07/10/2020
Apply by:08/11/2020
Job Reference:8845

Role Description


A fixed term postdoctoral appointment is available, for up to 24 months (with the possibility of extension) starting 1 January 2021 or as soon as possible thereafter, in the Department of Chemistry, to work in the groups of Professors Gideon Grogan and Ian Fairlamb. You will conduct research on enzyme-catalyzed amide bond formation, with an emphasis on the engineering of enzymes for the scaleable synthesis of pharmaceutical amides. The work is funded by the EPSRC and is supported by GSK.

The Department of Chemistry is one of the largest and most successful departments at York and we are renowned internationally for our research. As a department, we strive to provide a working environment that allows all staff and students to contribute fully, to flourish, and to excel. We are proud of our Athena SWAN Gold Award.


You will focus on research on enzyme-catalysed amide bond synthesis, specifically research into novel classes of amide bond forming enzymes for the synthesis of pharmaceutical amides. You will employ synthetic organic chemistry, gene cloning, expression, mutation and analytical techniques to characterise novel enzyme activity and look to develop scaleable processes for enzyme-catalysed amide bond formation.

Where appropriate you will:

  • conduct individual and collaborative research projects
  • assist in the identification and development of potential areas of research and the development of research proposals
  • provide guidance to other staff and students, as required, as well as coordinating the work of small research teams
  • analyse and interpret research data
  • write up research results and disseminate them through publications, seminar and conference presentations and public engagement and outreach activities
  • assist with undergraduate teaching in own area of expertise

Skills, Experience & Qualification needed

The successful candidate should have

  • A first degree in Biochemistry, Chemistry or a related discipline and a PhD with experience in synthetic organic chemistry and molecular biology (or have submitted a PhD thesis prior to taking up appointment)
  • A proven research track-record and knowledge of both synthetic and analytical organic chemistry relevant to catalysis and biocatalysis and knowledge of a range of research techniques and methodologies in molecular biology and enzymology
  • A good knowledge of and enthusiasm for contemporary research in applied biocatalysis
  • Skills in synthetic organic chemistry, gene cloning and protein production and analytical techniques associated with organic chemistry.
    • Experience of conducting independent and collaborative research projects and working as part of a harmonious research team
    • Highly developed communication skills, both orally and in writing, including publication in journals and competency to deliver presentations at conferences
    • Self-motivated with the ability to plan and prioritise own work in order to meet deadlines
    • A collaborative ethos and a willingness to proactively support colleagues and students

Interview date:

For informal enquiries: please contact Professors Gideon Grogan ( or Ian Fairlamb (

The Department of Chemistry values all employees for the qualities and skills they bring to the workplace and aims to be a diverse and egalitarian community in which all can thrive

The University is committed to promoting a diverse and inclusive community  – a place where we can all be ourselves and succeed on merit. We offer a range of family friendly, inclusive employment policies, flexible working arrangements, staff engagement forums, campus facilities and services to support staff from different backgrounds.

A place where we can ALL be ourselves #EqualityatYork

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