Postdoctoral Associate in Single-Cell Genomic Analyses of Lineage Relationships and Mutation Rates in Maize

Cornell University

United States

Postdoctoral Associate | Single-Cell Genomic Analyses of Lineage Relationships and Mutation Rates in Maize | Plant Biology | CALS

Single-Cell Genomic Analyses of Lineage Relationships and Mutation Rates in Maize.
 
Position Function

A Postdoctoral Associate Position is immediately available to join the Scanlon Lab (http://scanlonlab.plantbio.cornell.edu/) in the Plant Biology Section, School of Integrative Plant Science at Cornell University in the area of plant computational developmental biology. This position requires an experienced scientist to work on a collaborative project that investigates two, related big-picture questions in plant development: (1) How do plants allocate their cell divisions and mutations across their tissues and meristems to escape the accumulation of deleterious mutations in the germline, when germline identity is acquired late in plant development?; and (2) what are the cell-lineage relationships of all the cells, tissues and organs in the maize shoot? Novel genomic approaches now enable investigations of these phenomena at single-cell resolution. Responsibilities will include independent research in applying and designing new approaches to use CRISPR/Cas9-induced editing of transgenic target sequences to genetically mark every cell in the plant, and investigate the cell lineage relationships among distinct cells, tissues and organs. In addition, whole genome sequence analyses of individual plant cells will be analyzed throughout ontogeny to generate a mutational fate map of the maize plant and determine the modes and tempo of mutation in distinct, tissues, organs and cell lineages.
 
Position requirements

• Ph.D. with research experience in plant biology, bioinformatics, genomics, computational biology, statistics or related discipline.
• Proficiency in collecting and analyzing data sets.
• Excellent interpersonal and communication skills with a strong publication record.
• Independence and project leadership skills.
 
Preferred qualifications

• More than 3 years of experience in computational biology, bioinformatics, and genomic analyses.
• Extensive experience in genomic sequence analyses transcriptomics, and statistical analyses
• Experience in plant phylogenomics.
• A record of publication in the field of plant computational genomics.
• Experience in plant developmental biology
 
Supervision Exercised

The position may include some supervision of undergraduate and graduate students involved in research on the project.
 
Anticipated Division of Time

Data generation and collection: GESTALT analyses, single cell RNAseq, single-cell/tissue sequencing 40%
Data analyses and evaluation 45%
Participation in preparation of annual reports and publications 15%
 
How to Apply

A letter of interest in the position, C.V., diversity statement and contact information for three references should be submitted on-line via the Academic Jobs Online posting: 
https://academicjobsonline.org/ajo/jobs/16618.
 
Review of applications will begin immediately and continue until the position is filled.

Employment Assistance:

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For general questions about the position or the application process, please contact the Recruiter listed in the job posting.

Applicants that do not have internet access are encouraged to visit your local library, or local Department of Labor. You may also visit the office of Workforce Recruitment and Retention Monday - Friday between the hours of 8:30 a.m. – 4:30 p.m. to use a dedicated workstation to complete an online application.

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