Postdoctoral Fellow in Bioinformatics and Antibiotic Resistance

University of Gothenburg

Sweden

 

Subject Description

Most resistance genes that cause problems in health care today appear to originate from harmless environmental bacteria. Our group is studying the driving forces behind this development, particularly how low levels of antibiotics can affect processes such as mobilization of resistance genes, mutation rate, horizontal gene transfer, selection and transmission of resistance between environments. In some sub-projects we study the evolutionary relationships between resistance genes in environmental bacteria and pathogens, and look for new forms of resistance in different environments using both bioinformatic methods and various large-scale functional analyzes. Knowledge of which resistance factors health care may encounter tomorrow is valuable for quickly managing new threats. We are looking for a postdoctor who wants to take on the task of exploring different environments with previously unknown, mobile resistance factors and in collaboration with colleagues to characterize these with bioinformatic models. Other issues that are relevant pertain to the risk of spread of resistant bacteria through the environment, as well as the risk that the release of selective agents into the environment drives the evolution of new resistance factors.


Duties

The postdoctor is expected to conduct studies aimed at identifying mobile resistance genes previously not described in pathogens. In addition to identifying and expressing these genes, the tasks may include characterizing their evolution, function, structure (in collaboration with microbiologists, molecular biologists and structural chemists), regulation, expression, mobility, and occurrence in different species and environments. The work may also include other aspects of the development, occurrence and spread of antibiotic resistance in other ongoing projects in the group. One such project is to quantify the risks of spreading resistance to workers and residents living around municipal sewage treatment plants, using both metagenomic and genomic sequence data of bacteria / bacterial communities in water, air and faeces.


Competence

Eligible to be hired as a postdoctoral student is the one who holds the doctoral degree in the relevant subject area at the last application date. Since employment as a postdoctoral student is a qualifying position for junior researchers, we are directed to the person who holds a doctoral degree that is not older than 3 years from the last application date.

Eligibility for employment as a teacher is specified in Chapter 4, Section 3 - 4 of the Higher Education Ordinance and the University of Gothenburg's own employment scheme.


Basis of Assessment

Doctoral degree in relevant area as well as good scientific production in relevant area in relation to the time elapsed since the doctorate was passed are requirements. Strong merit is high independence including experience in bioinformatic work with bacterial genomes and metagenomics, development and validation of models to identify resistance genes, programming in relevant programming languages (eg python), broad experience in various bioinformatic tools, excellent communicative ability, especially with regard to to express themselves scientifically in writing and orally in English, a developed scientifically critical approach, and the ability to work successfully in a group. 

Assessment bases for hiring as a teacher are set out in Chapter 4, sections 3 - 4 of the Higher Education Ordinance and the University of Gothenburg's own employment scheme.


Employment

The position is full-time and time-limited, two years, with placement until further notice at the Department of Biomedicine. Entry is by agreement. 


Contact Details for the Position

Information about the position is provided by Professor Joakim Larsson, e-mail: joakim.larsson@fysiologi.gu.se


Unions

Trade union representatives at the University of Gothenburg can be found here: http://www.gu.se/omuniversitetet/aktuellt/lediga-job/ union-contacts


Application

You apply for the job via the University of Gothenburg's recruitment portal by clicking on the "Apply" button. You as the applicant are responsible for ensuring that the application is complete in accordance with the advertisement and that it is submitted to the university by the last application date.

The application must contain:

  • A personal letter explaining why you are seeking the service
  • CV that includes scientific publications
  • Copy of proof of doctoral degree
  •  Two references with contact details


In your application, please refer to Professorpositions.com

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