Postdoctoral Fellow in Biology

University of Pennsylvania – Penn Lung Biology Institute

Description

Mentor: Michael F. Beers, MD
Department: Pulmonary and Critical Care Medicine
Funding Sources: NIH, Department of Veterans Affairs, and Endowment
Open to: U.S. Citizens and Foreign Nationals

The Lung Epithelial Biology Laboratory at the Penn Lung Biology Institute (LBI), under the direction of Dr. Michael Beers, has an exceptional opportunity available for Postdoctoral Fellows to join a collaborative research project directed at unraveling the mysteries of idiopathic pulmonary fibrosis and other parenchymal lung diseases.

The Beers Lab has an existing program funded by NIH, the Department of Veterans Affairs, private foundations, and industry to study the molecular mechanisms that regulate tissue injury and repair in focused on discovery, target ID, target validation, and proof or principal studies aimed at uncovering and exploiting novel pathways to treat fibrotic lung diseases. The postdoctoral fellow can focus the project in any of several related areas (epithelial biology, immunological networks, metabolomics, epithelial-mesenchymal crosstalk, and/or transcriptomics/proteomics) using 2 novel published models of lung injury and fibrosis (see https://www.ncbi.nlm.nih.gov/pubmed/29920187; https://www.ncbi.nlm.nih.gov/pubmed/30910861; https://www.ncbi.nlm.nih.gov/pubmed/30721158).

In addition to the unique mouse reagents, the successful candidate will have access to a variety of cutting-edge technologies including RNAseq, single cell and ATAC RNAseq, high resolution proteomics, CRISPR mediated screens, lineage tracing, organoid assays, and iPS cells to identify pathways critical for lung tissue repair and regeneration. The ideal candidate will have an M.D., Ph.D. or MD/PhD with a strong background in basic molecular and cell biology skills. Experience utilizing mouse models and primary cell culture systems is required for the success of this position.

Qualifications

Qualifications and Requirements

• PhD in Cell Biology, Biochemistry, Immunology, or related Biomedical Fields

• Solid background in molecular biology, biochemistry, genetics and cell biology

• Hands-on experience with animal models, mammalian tissue culture, molecular biology techniques and tissue imaging procedures are required

• Excellent record of publications in highly respected international scientific journals

• Familiarity with advanced imaging techniques, transcriptomic profiling, flow cytometry, and/or bioinformatics is desirable

Application Instructions

To apply for this position, applications should also be uploaded in Interfolio with the link provided.

In addition, please email mfbeers@pennmedicine.upenn.edu with the subject line “Postdoctoral Fellow Lung Biology” and attach the following items:

• Current CV

• Cover letter

In your application, please refer to Professorpositions.com