Research Associate / Fellow in Pharmacy

University of Nottingham Department of Pharmacy

United Kingdom

Research Associate/Fellow (fixed term)

Reference
SCI267520
Closing Date
Friday, 30th October 2020
Job Type
Research
Department
Pharmacy
Salary
£27511 to £33797 per annum, (pro rata if applicable) depending on skills and experience (minimum £30942 with relevant PhD). Salary progression beyond this scale is subject to performance

Applications are invited for a researcher to work on an MRC/Newton Fund/NAFOSTED- funded project aimed at creating an innovative targeted liposomal delivery system for the treatment of antibiotic resistant Helicobacter pylori infections.

Helicobacter pylori (Hp) infects half of the world's population and is the leading cause of gastric ulcers and cancer. While the prevalence has declined steadily in high income countries, due to appropriate hygienic standards and the existence of various first line or rescue therapies, it remains very high in low income countries. In many Asian countries, including Vietnam, gastric cancer is a leading cause of death. Additionally, there is a rising failure of drugs to eradicate Hp infections due to steadily increasing antimicrobial resistance. Important drugs commonly used for first line treatment of Hp, such as Metronidazole and Clarithromycin, are becoming obsolete in Vietnam. We are aiming to create an efficient drug delivery platform which can be used to combat the increasing resistance of Hp as the leading cause of gastric cancer in Vietnam (and elsewhere in low income countries).

The appointed researcher will work on an exciting new project in the context of an international collaboration between the University of Nottingham (UK), the 108 Military Central Hospital in Hanoi (Vietnam), and the Justus-Liebig- University of Giessen (Germany). Candidates must have excellent experience with recombinant protein expression and purification, standard molecular biology or biochemical techniques. Experience with functionalisation of liposomes is highly desirable. Experience with confocal laser microscopy is an advantage and/or specialised in vivo imaging techniques (e.g.Tc-99m NanoSPECT-CT imaging) is desirable.

In addition to the daily research activities, the appointed researcher will be responsible for facilitating information exchange between the collaborating centres, will be involved in organising and delivering a training school in Vietnam and will also coordinate and organise regular visits between the collaborating partners in the UK and Vietnam. Therefore, knowledge of the Vietnamese language is not only desirable, but an important advantage.  

The researcher will be working with an academic at each of the research institutions to deliver the project.

Candidates must hold a PhD (or be near to completion), or equivalent in Chemistry, Biochemistry, Biology, Pharmacy, Pharmacology or related areas.

This full-time (36.25 hours per week) post is available immediately and will be offered on a fixed-term contract until 30 January 2023.

Our University has always been a supportive, inclusive, caring and positive community. We warmly welcome those of different cultures, ethnicities and beliefs – indeed this very diversity is vital to our success, it is fundamental to our values and enriches life on campus. We welcome applications from UK, Europe and from across the globe. For more information on the support we offer our international colleagues, visit; https://www.nottingham.ac.uk/jobs/applyingfromoverseas/index2.aspx

Informal enquiries may be addressed to Dr Sebastiaan Winkler (Sebastiaan.Winkler@nottingham.ac.uk) or Prof Franco H. Falcone (Franco.Falcone@vetmed.uni-giessen.de). Please note that applications sent directly to these email addresses cannot be accepted.

Our University has always been a supportive, inclusive, caring and positive community. We warmly welcome those of different cultures, ethnicities and beliefs – indeed this very diversity is vital to our success, it is fundamental to our values and enriches life on campus. We welcome applications from UK, Europe and from across the globe. For more information on the support we offer our international colleagues, visit; https://www.nottingham.ac.uk/jobs/applyingfromoverseas/index2.aspx

For all successful international applicants, including EU/EEA applicants from January 2021, we offer an interest-free loan to help cover the cost of immigration-related expenses to the UK, including visas and the NHS surcharge. For more information follow this link https://www.nottingham.ac.uk/hr/guidesandsupport/workingintheuk/documents/support-with-immigration-expenses-policy-application-form.pdf

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