Research Associate in Biological Sciences

University of Cambridge

United Kingdom

Applications are invited for two Research Associate posts in Professor Sarah Bray's research group. You will work in a collaborative, multidisciplinary team investigating Notch regulatory networks in development and their relevance to disease. One project will focus on epigenetic mechanisms that remodel enhancers during cell fate transitions to programme the correct response to signalling (for example to maintain stem cells or promote differentiation depending on the context) and that enable enhancers to select the correct promoter. The other project will investigate how Notch signals are decoded in real time in vivo and will involve live-imaging of transcription and of nuclear complexes, including single molecule tracking of transcription factors in living tissues. The projects build on exciting assays we have recently developed (Falo Sanjuan et al., 2019, Dev Cell 50:411-425.e8; Gomez-Lamarca et al., 2018, Dev Cell 44:611-623.e7) and will involve generating new tools, including optogenetics, through genome editing and other approaches.


We are looking to recruit highly motivated scientists with strong investigative skills. You should have a PhD (or soon to be awarded your PhD) and experience in one or more of the following: molecular biology, epigenetics, developmental biology, cell biology Drosophila genetics. Experience of genome-wide transcriptional analysis would be an advantage for one position and of advanced imaging and image analysis for the other.


Further information about research in the Bray group can be found at: http://www.pdn.cam.ac.uk/staff/bray_s/index.shtml. For informal enquiries, please email Prof Bray at: sjb32@cam.ac.uk.


Fixed-term: The funds for this post are available for 3 years in the first instance.


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Please ensure that you upload your Curriculum Vitae (CV) and a covering letter in the Upload section of the online application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.


Please quote reference PM22144 on your application and in any correspondence about this vacancy.


The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.


The University has a responsibility to ensure that all employees are eligible to live and work in the UK.


In your application, please refer to Professorpositions.com

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