Research Associate in Evolution of Specialised Plant Metabolites in the Caryophyllales

University of Cambridge

United Kingdom

The Brockington Lab ( at the University of Cambridge is looking to hire a postdoctoral research associate to work on the evolution of specialised plant metabolites in the Caryophyllales. This NSF-DEB-NERC-funded project is a collaboration with Hiroshi Maeda at the University of Wisconsin-Madison (metabolite and enzyme analyses), Stephen Smith at the University of Michigan (evolutionary modelling), and Ya Yang at the University of Minnesota (phylo-trasncriptomics).

Our research is interdisciplinary - combining in vitro protein characterisation, in planta transgenic assays, site-directed mutagenesis, phylogenetics, transcriptomics, and genomics. We are looking to deepen our understanding of the residue-level evolution of key enzymes in the betalain pathway, to move from single gene to whole network analyses, and to expand our understanding of the regulation of the betalain pathway. We seek candidates with an excellent background in "wet-lab' approaches to plant specialised metabolism, to complement a strong bioinformatics team. In particular we are interested in candidates with broad capabilities in molecular biology, and particular expertise in in vitro protein characterisation, in planta transgenics, and HPLC/GCMS. Experience working with Nicotiana benthamiana and Saccharomyces cerevisiae would be very desirable. Experience in transcriptional network approaches to plant metabolism, and techniques such as SELEX or DAPseq would be an added bonus.

Please see further details document for additional information on the post. To apply please upload your CV, publication list and covering letter.

Fixed-term: The funds for this post are available for 2 years in the first instance.

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For any queries on the position please contact Del Hawtin Please notice that if you have not received any news from us 1 month after the closing date you should consider that on this occasion your application has not been successful.

Please quote reference PD23096 on your application and in any correspondence about this vacancy.

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