Research Associate in Neuroepigenomics

Imperial College London Department of Brain Sciences

United Kingdom

Job summary

The UK Dementia Research Institute (UK DRI) at Imperial has been established to address a medical research area of the highest importance and future impact. As one of seven national centres of excellence embedded in major UK universities, we intend to transform the diagnosis, treatment and care of people with dementias. The Medical Research Council and charity partners the Alzheimer's Society and Alzheimer’s Research UK have invested £290m...

Job listing information

  • Reference MED02069
  • Date posted 15 October 2020
  • Closing date 15 November 2020

Key information about the role

  • Location White City Campus (map)
  • Position type Full time, fixed term
  • Salary £40,215 – £47,579 plus benefits
  • Department Department of Brain Sciences
  • Category Researcher / Non Clinical Researcher

Job description

Job summary

The UK Dementia Research Institute (UK DRI) at Imperial has been established to address a medical research area of the highest importance and future impact. As one of seven national centres of excellence embedded in major UK universities, we intend to transform the diagnosis, treatment and care of people with dementias. The Medical Research Council and charity partners the Alzheimer's Society and Alzheimer’s Research UK have invested £290m in fulfilment of the ambition identified in the Prime Minister's 2020 Challenge on Dementia.

The fellowship programme of Dr Alexi Nott is focused on defining how the epigenome regulates cell type specific gene expression programs in aging-related brain disorders using next-generation sequencing of patient-derived brain tissue and stem cell models of disease. These studies will help to guide the functional interpretation of noncoding disease risk variants for aging-related brain disorders such as Alzheimer’s disease.

The UK DRI is seeking an outstanding post-doctoral researcher interested in taking on a challenging role with considerable scope for independent scientific achievement and personal growth.

Duties and responsibilities

You will be expected to help to define specific research programmes within this remit and undertake these in conjunction with colleagues in multi-disciplinary teams. Considerable independence is expected, with anticipation of a growing role in leadership of the research.  In addition, you will be expected to submit publications to refereed journals and to join in attracting external research funding.

There will be opportunities for supervision of students. Experience in other teaching roles, including lecturing, will be enabled as part of the broad range of career development opportunities that Imperial College makes available to its post-doctoral research staff.

Essential requirements

You will be ambitious, with the passion to tackle big problems and a readiness to try out high-risk, high-payoff projects. Exceptional experience of genomic approaches, preferentially those pertaining to chromatin biology, is desirable and a background in molecular neuroscience would be advantageous.

Further information

The contract is offered full time, initially for a fixed term until 31 December 2024.

Candidates who have not yet been officially awarded their PhD will be appointed as a Research Assistant within the salary range £35,477 - £38,566 per annum.

Applicants are strongly encouraged to contact Dr Alexi Nott for informal discussion about the role at a.nott@imperial.ac.uk

For more information about the UK DRI at Imperial, please visit: http://www.imperial.ac.uk/dementia-research-institute

Dr Nott’s research website: https://nottgroup.com/

The UK Dementia Research Institute: https://ukdri.ac.uk/

Should you have queries about applying for the role, please contact Dr Jennifer Podesta j.podesta@imperial.ac.uk

For technical issues when applying online please email recruitment@imperial.ac.uk

The College is a proud signatory to the San-Francisco Declaration on Research Assessment (DORA), which means that in hiring and promotion decisions, we evaluate applicants on the quality of their work, not the journal impact factor where it is published. For more information, see https://www.imperial.ac.uk/research-and-innovation/about-imperial-research/research-evaluation/

The College believes that the use of animals in research is vital to improve human and animal health and welfare. Animals may only be used in research programmes where their use is shown to be necessary for developing new treatments and making medical advances. Imperial is committed to ensuring that, in cases where this research is deemed essential, all animals in the College’s care are treated with full respect, and that all staff involved with this work show due consideration at every level. http://www.imperial.ac.uk/research-and-innovation/about-imperial-research/research-integrity/animal-research/


In your application, please refer to Professorpositions.com

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