Research Associate in Translational Neuroscience

University of Pennsylvania Perelman School of Medicine

United States

Description

The Department of Neurology at the Perelman School of Medicine at the University of Pennsylvania seeks candidates for a Research Associate position in the Academic Support Staff. This appointment will be initially for one (1) year and continuation during that time period and renewal are based on satisfactory performance and availability of funding (limited to three (3) years). Expertise is required in the specific area of Prior experience in two or more of the skills listed in the description is preferred. Applicants must have a Ph.D. or M.D./Ph.D. degree.

Responsibilities may include The Jensen laboratory is seeking a qualified applicant for a Research Associate. The focus of the laboratory is the study of synaptic dysfunction during the lifespan, with special relevance to epilepsy and its cognitive comorbidities. The interaction between hyperexcitable network mechanisms in epileptogenesis with those in other disorders are a current focus. Research projects in the lab span understanding the role of excitatory and inhibitory synaptic imbalance in autism, epilepsy, and dementia. A variety of experimental models ranging from in vitro brain slice, cell culture, and transgenic mouse models are used. A parallel emphasis on systems neuroscience and cellular neuroscience is employed. Human tissue studies from epilepsy biopsy samples and post mortem studies complement the animal work in order to provide target validation and clinical relevance. Research tools employed include gene and protein expression assays, in vitro brain slice patch clamp and extracellular electrophysiology, voltage sensitive dye and calcium imaging, gene therapy preclinical studies, systems study of behavior and video electroencephalographic (EEG) quantitation, and well as immunohistopathological studies of brain and cell culture samples.

The successful applicant will have an opportunity to engage in a vibrant educational environment, with an emphasis on multidisciplinary collaboration. The Jensen lab collaborates with a range of other laboratories, and thus the candidate must demonstrate the ability to collaborate and also communicate well with those in other fields. Teaching skills are also preferred, as the applicant will be expected to supervise graduate student as well as research technicians in the course of their work.

We seek candidates who embrace and reflect diversity in the broadest sense. The University of Pennsylvania is an EOE. Minorities/women/individuals with disabilities/protected veterans are encouraged to apply.


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