Research Associate in Trophoblast Research

University of Cambridge

United Kingdom

We are looking for a highly motivated and talented bioinformatician to join the teams of Dr. Margherita Turco and Prof. Ashley Moffett as a postdoctoral research associate. The central aim of our lab is to understand the critical events underlying the establishment of pregnancy in humans by investigating how the human placenta develops and how this process is influenced by the maternal uterine microenvironment.

The research associate will investigate the lineage relationships between the different cell types of the early human placenta by developing computational tools and methods to analyse our experimental datasets from single cell RNA sequencing and live-imaging experiments of organoids and placental tissue. The postholder will work closely together with members of the lab that perform the experimental work and will play a leading role in experimental design, data analysis and visualisation and interpretation. This project is funded by the Wellcome Trust and is in collaboration with Dr. Russell Hamilton at the Department of Genetics, University of Cambridge.

Candidates will have a strong computational background with experience in single-cell transcriptomic analysis and imaging data. The position requires a Ph.D (awarded or imminent) in bioinformatics, mathematics/statistics or other relevant computational background. Background in reproductive/placental biology is not essential and candidates keen to gain experience from another field are encouraged to apply. Excellent programing/scripting skills in R, Python, Fiji plugins etc. are needed. Experience with data processing in an HPC cluster environment and an understanding of hierarchical storage systems will be important as the postholder will also play a leading role in the data management strategy of the Turco Lab.

The successful candidate is a motivated, committed individual who enjoys working as part of a collaborative and multidisciplinary team. Strong work ethics, critical thinking and excellent communication skills are essential.

We are affiliated with the Centre for Trophoblast Research https://www.trophoblast.cam.ac.uk/ and The Wellcome Trust - Medical Research Council Cambridge Stem Cell Institute (CSCI) https://www.stemcells.cam.ac.uk/. Please visit our lab websites at www.turcolab.org and https://www.trophoblast.cam.ac.uk/people/Russell-Hamilton for more information.

For informal enquiries please contact Dr. Margherita Turco, myt25@cam.ac.uk and Dr. Russell Hamilton rsh46@cam.ac.uk.

Fixed-term: The funds for this post are available for 2 years in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

Applications are welcome from internal candidates who would like to apply for the role on the basis of a secondment from their current role in the University.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

General queries regarding the position should be directed to HR@path.cam.ac.uk

Please quote reference PK24327 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

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