Research Associate in Tumour Organoids-on-Chip

Imperial College London Department of Bioengineering

United Kingdom

Job summary

This is a highly collaborative opportunity to develop next generation microfluidics organ-on-chip technologies for addressing pressing needs in cancer. You will join a highly multidisciplinary team of leading researchers at Imperial College London, the Institute of Cancer Research and the Francis Crick Institute.   Cancer organoids are a model of choice to evaluate basic tumour biology and in applications such as drug screening and...

Job listing information

  • Reference ENG01641
  • Date posted 9 April 2021
  • Closing date 9 May 2021

Key information about the role

  • Location South Kensington Campus (map)
  • Position type Full time, fixed term
  • Salary £40,858 – £48,340 plus benefits
  • Department Department of Bioengineering
  • Category Researcher / Non Clinical Researcher

Job description

Job summary

This is a highly collaborative opportunity to develop next generation microfluidics organ-on-chip technologies for addressing pressing needs in cancer. You will join a highly multidisciplinary team of leading researchers at Imperial College London, the Institute of Cancer Research and the Francis Crick Institute.  

Cancer organoids are a model of choice to evaluate basic tumour biology and in applications such as drug screening and development. However, their adoption and utility has been limited by a) poor derivation rates for many tumour types and b) added complexity to maintain and study organoid cultures. As the bioengineering experimental lead on this project, you will be tasked to address both roadblocks through the development of microfluidic tumour organoid-on-chip devices.

This project is generously funded by the Cancer Research UK Convergence Science Centre (https://www.convergencesciencecentre.ac.uk/), whose aim is to bring together leading physical scientists, biologists and clinicians to solve urgent challenges in cancer. You will be hosted at Imperial College, but will meet regularly with all team members over the duration of the project.

After completion of the term, you will be well equipped for in-demand careers with many of the following skills: cell & tissue culture, cancer biology, microscopy, molecular techniques, organ-on-a-chip, drug screening, cleanroom microfabrication, computer-assisted design, statistical analysis, computational modelling, scientific writing/presentation skills and project management.

Another exciting research associate post is currently available in the Au Lab , visit www.imperial.ac.uk/jobs and search by the job reference ENG01639. Qualified candidates are encouraged to apply to both posts if interested. 

Duties and responsibilities

    • To take plan and conduct laboratory experiments
    • To collaborative effectively within and across research groups, including providing guidance to students
    • To maintain highly organised and accurate record of experimental work.
    • To publish in high quality journals and to present data at national and international conferences
    • To contribute to the smooth running of laboratories and facilities

Essential requirements

    • A PhD in Engineering, Biology, or a closely related discipline, or equivalent research, industrial or commercial experience.
    • Practical experience within a research environment and/or publication in relevant and refereed journals
    • Experimental experience in at least one of microfluidics, microfabrication, cell biology or cancer
    • Experience in both microfluidics and life sciences is desired, but not essential as relevant training will be provided

Further information

This post is full time and fixed term until 31 March 2022. A contract renewal is subject to grant renewal of the CRUK Convergence Science Centre.

Candidates who have not yet been officially awarded their PhD will be appointed as a Research Assistant within the salary range £36,045 - £39,183 per annum.

Closing date: 09 May 2021

For informal enquiries about the post, please contact Dr Sam Au at s.au@imperial.ac.uk . Further information can be found at www.biomicrotech.science

We are committed to equality of opportunity, to eliminating discrimination and to creating an inclusive working environment for all. We therefore encourage candidates to apply irrespective of age, disability, marriage or civil partnership status, pregnancy or maternity, race, religion and belief, gender identity, sex, or sexual orientation. We are an Athena SWAN Silver Award winner, a Disability Confident Leader and a Stonewall Diversity Champion

The College is a proud signatory to the San-Francisco Declaration on Research Assessment (DORA), which means that in hiring and promotion decisions, we evaluate applicants on the quality of their work, not the journal impact factor where it is published. For more information, see https://www.imperial.ac.uk/research-and-innovation/about-imperial-research/research-evaluation/

The College believes that the use of animals in research is vital to improve human and animal health and welfare. Animals may only be used in research programmes where their use is shown to be necessary for developing new treatments and making medical advances. Imperial is committed to ensuring that, in cases where this research is deemed essential, all animals in the College’s care are treated with full respect, and that all staff involved with this work show due consideration at every level. http://www.imperial.ac.uk/research-and-innovation/about-imperial-research/research-integrity/animal-research


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