Research Associate/Fellow in Protein Crystallography

University of Nottingham Department of Pharmacy

United Kingdom

Research Associate/Fellow in Protein Crystallography (fixed term)

Reference
SCI015821
Closing Date
Friday, 12th March 2021
Job Type
Research
Department
Pharmacy
Salary
£27511 to £31866 per annum, (pro rata if applicable) depending on skills and experience (minimum £30942 with relevant PhD).

We are currently seeking a postdoctoral scientist to join a multi-disciplinary collaborative MRC funded translational research programme involving microbiologists, medicinal chemists, and clinicians to characterise the molecular mode of action of a novel agent targeting Clostridium difficile infection (CDI). The project will explore the structure and biophysics of agent - protein target interactions using complementary techniques. CDI is a serious global public health threat, and is associated with significant morbidity, mortality and healthcare resource utilisation. The US CDC has recently classified this "superbug" among the serious immediate antibiotic-resistant infectious public health threats that require immediate and aggressive action. 

The successful candidate will be responsible for the determination of a high-resolution structure of the protein target in complex with the novel agent in combination with a thorough biophysical characterisation of the interaction.

Candidates must have a PhD submitted or awarded in protein crystallography and a track record of successful recombinant protein construct design, crystallisations and 3D structure determination.  Skills in analysing interactions between proteins and ligands using complementary biophysical techniques is also essential.  

This full-time post will be offered on a fixed-term contract for a period of 12 months. There is a funding end date of 31 March 2022. Job share arrangements may be considered. 

We pride ourselves on the collegial and supportive culture created by our staff for our staff and students. We are dedicated to providing an environment which enables our staff to thrive and achieve their potential. Our commitment to Equality and Diversity has been recognised in the award of an?Athena SWAN Silver Award. 

Informal enquiries may be addressed to Dr Ingrid Dreveny (email: Ingrid.dreveny@nottingham.ac.uk). Please note that applications sent directly to this email address will not be accepted.

Our University has always been a supportive, inclusive, caring and positive community. We warmly welcome those of different cultures, ethnicities and beliefs – indeed this very diversity is vital to our success, it is fundamental to our values and enriches life on campus. We welcome applications from UK, Europe and from across the globe. For more information on the support we offer our international colleagues, visit; https://www.nottingham.ac.uk/jobs/applyingfromoverseas/index2.aspx

For all successful international applicants, including EU/EEA applicants from January 2021, we offer an interest-free loan to help cover the cost of immigration-related expenses to the UK, including visas and the NHS surcharge. For more information follow this link https://www.nottingham.ac.uk/hr/guidesandsupport/workingintheuk/documents/support-with-immigration-expenses-policy-application-form.pdf

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