Research Fellow in Membrane Protein Biochemistry and Cryo-EM

Monash University


Research Fellow (Membrane Protein Biochemistry and Cryo-EM)

Job No.: 614321

Location: Parkville campus

Employment Type: Full-time 

Duration: 12-month fixed-term appointment

Remuneration: $69,401 - $94,190 pa Level A (plus 9.5% employer superannuation)

  • Be inspired, every day
  • Drive your own learning at one of the world’s top 80 universities
  • Take your career in exciting, rewarding directions

Everyone needs a platform to launch a satisfying career. At Monash, we give you the space and support to take your career in all kinds of exciting new directions. You’ll have access to quality research, infrastructure and learning facilities, opportunities to collaborate internationally, as well as the grants you’ll need to publish your work. We’re a university full of energetic and enthusiastic minds, driven to challenge what’s expected, expand what we know, and learn from other inspiring, empowering thinkers.

Monash University strongly advocates diversity, equality, fairness and openness. We fully support the gender equity principles of the Athena SWAN Charter and invite you to join us in celebrating women in STEMM.

The Opportunity

Join with one of the world’s leading research groups applying structural biology and advanced analytical pharmacology approaches to tackle key questions on the function of G protein-coupled receptors (GPCRs), the largest family of membrane drug targets. The successful candidate will be part of innovative research integrating cryo-electron microscopy, pharmacology and computational chemistry to understand the interaction of natural ligands and drugs with their GPCR targets, how these interactions control signalling, and the application of this knowledge to novel drug discovery and development.

The candidate's responsibilities: You will apply your experience to the isolation of GPCRs that will be used for cryo-EM structure determination and/or biophysical and biochemical study of GPCR function. You will contribute to the determination of the structure of GPCRs and their complexes with drugs and signaling proteins using cryo-EM. You will work within a broader team integrating membrane protein biochemistry, high-resolution cryo-EM structure determination, molecular and analytical pharmacology and medicinal chemistry to understand and modulate GPCR function.

The candidate's attributes: You will have a PhD in an appropriate discipline and extensive experience in membrane protein biochemistry, preferably with additional specific expertise in structural characterisation of membrane proteins by cryo-EM. Specific experience working with GPCRs would be desirable. You will be able to work both independently and seamlessly within a larger team environment, including application of highly developed technical skills, and rapid ability to learn new techniques.

This role is a full-time position; however, flexible working arrangements may be negotiated.

At Monash University, we are committed to being a Child Safe organisation. Some positions at the University will require the incumbent to hold a valid Working with Children Check. 

Your application must address the selection criteria. Please refer to "How to apply for Monash Jobs".


Professor Patrick Sexton, Professor Pharmacology, Director, ARC Centre for Cryo-electron Microscopy of Membrane Proteins,

Position Description

Download FileResearch Fellow

Closing Date

Wednesday 3 March 2021, 11:55 pm AEDT

In your application, please refer to


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