Researchers in Biology
University of Helsinki
Finland
Group: Muhleip
Institute: HiLIFE – Institute of Biotechnology, University of Helsinki
Project Description
The research in the group is focused on understanding how protein complexes organise mitochondrial membranes in protozoan parasites and how membrane organization is disrupted in human mitochondrial disorders.
The successful applicant will work on the structural and functional characterisation of mitochondrial energy conversion complexes and remodelling in protozoan parasites using:
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Protein biochemistry
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Single-particle cryo-EM
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In-situ cryo-electron tomography
Specifically, the project is aimed at:
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Visualisation of inner-membrane architecture
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Characterising parasite-specific modulation of membrane biogenesis
Opportunities:
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Combine parasitology and mitochondrial biology with state-of-the-art structural biology techniques
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Access to a 200-kV Talos Arctica microscope in-house
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Access to 300-kV cryo-electron microscopes at international facilities
Recent publications from the group:
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Nature Communications: https://www.nature.com/articles/s41467-025-56057-9
About You
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Ambitious, goal-oriented, collegial, and motivated to tackle a challenging project
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High interest in learning structural biology methods (comprehensive cryo-EM training will be provided); prior experience beneficial
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Prior experience in parasitology cell culture and genetic engineering (malaria or kinetoplastid parasites) is greatly beneficial but not required
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Master’s degree (or final stage of obtaining degree) in cell/molecular biology, parasitology, protein biochemistry, structural biology, or a similar field
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Excellent command of English (working language at the institute)
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Strong communication, interpersonal, organizational, and time management skills
What We Offer
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A collaborative, innovative, and inclusive work environment
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Training in state-of-the-art methods in structural parasitology
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Doctoral education within the Integrated Life Sciences Doctoral Programme (ILS)
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Competitive salary depending on qualifications and performance
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5–7 weeks of holiday
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Flexible working hours
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Occupational health care and access to high-quality sports facilities
How to Apply
Applications in English should be submitted as soon as possible or no later than 30th September 2025. Applications will be continually reviewed. Positions are available immediately or according to mutual agreement.
Required application materials:
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Cover letter
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CV
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Contact details of three references
Contact for further information:
Alexander Mühleip – alexander.muhleip@helsinki.fi
About the Institute of Biotechnology, HiLIFE, University of Helsinki
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Independent research institute within the University of Helsinki Institute of Life Science (HiLIFE)
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Global forefront of life science research with state-of-the-art core facilities in genomics, biological imaging, and structural biology
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Ranked among the top 80 universities worldwide in life science research (Times Higher Education, 2024)
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Welcoming environment for international researchers, with support for relocation to Finland
Employee login for applications:
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For those with a helsinki.fi username and a valid employment, grant researcher, visiting researcher, or visiting professor contract at the University of Helsinki
Deadline: 30.09.2025
Unit: Helsinki Institute of Life Science
Sub-unit: Institute of Biotechnology
ID: 4256
Working for the World
Science has the power to change the world. Join one of the best research universities in the world – an international community united through bold thinking, science, research, and learning, with over 30,000 students and 8,000 employees.
Our approach:
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Multidisciplinary research
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Cross-border collaboration
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Dedication to real-world solutions and sustainable futures
Values: truth, bildung, freedom, inclusivity, and passion for meaningful work
Join us: Work for the future – work for the world
Questions: See the recruitment system FAQ
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